ICA 110381

CAS No. 325457-99-6

ICA 110381( —— )

Catalog No. M20949 CAS No. 325457-99-6

ICA 110381 is a KCNQ2/Q3 potassium channel opener for the treatment of epilepsy.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 43 Get Quote
5MG 71 Get Quote
10MG 111 Get Quote
25MG 191 Get Quote
50MG 285 Get Quote
100MG 428 Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    ICA 110381
  • Note
    Research use only, not for human use.
  • Brief Description
    ICA 110381 is a KCNQ2/Q3 potassium channel opener for the treatment of epilepsy.
  • Description
    ICA 110381 is a KCNQ2/Q3 potassium channel opener for the treatment of epilepsy.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    Potassium Channel
  • Recptor
    KCNQ2/Q3 potassium channel
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    325457-99-6
  • Formula Weight
    267.11
  • Molecular Formula
    C12H8Cl2N2O
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O=C(Nc1ccc(Cl)nc1)c1ccc(Cl)cc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Amato G Roeloffs R Rigdon G C et al. N-Pyridyl and Pyrimidine Benzamides as KCNQ2/Q3 Potassium Channel Openers for the Treatment of Epilepsy[J]. ACS Medicinal Chemistry Letters 2011 2(6):481.
molnova catalog
related products
  • Linoleoyl glycine

    Linoleoyl glycine, a modified polyunsaturated fatty acid, is an endogenous homologue of linoleoyl glycine. Linoleoyl glycine activates human KCNQ1/KCNE1 (hKCNQ1/hKCNE1) channels expressed in xenopus oocytes from mammalian skin.

  • AUT1

    AUT1 (AUT-1) is a novel specific modulator of Kv3 channels (EC50: 4.7 and 4.9 uM for Kv3.1b and Kv3.2a).

  • 5-Hydroxydecanoate s...

    5-Hydroxydecanoate sodium is a selective ATP-sensitive K+ (KATP) channel blocker with an IC50 of approximately 30 μM and a substrate for mitochondrial outer membrane acyl-CoA synthetase, possessing antioxidant properties.